Hyperpigmentation is a common skin condition characterized by darkened areas on the skin, such as dark patches on the face, hyperpigmentation around the mouth, or uneven skin pigmentation. This condition can affect any part of the body, including the face, neck, underarms, and even the inner thighs and buttocks. “The good news is that there are several effective treatments available for managing and reducing hyperpigmentation, including laser treatments, chemical peels, and more”, says Dr. Niketa Sonavane, top dermatologist in Mumbai, India and founder of Ambrosia Aesthetics. In this article, we will explore the various causes of hyperpigmentation and discuss the best treatment options available to help you achieve clearer, more even-toned skin.

Dr. Niketa Sonavane
Dermatologist, Skin Specialist and Hair Specialist practicing in Mumbai with over 17 years experience and over 10,000 happy patients.
Understanding Hyperpigmentation
What Causes Hyperpigmentation?
Hyperpigmentation occurs when an excess of melanin, the pigment responsible for skin color, forms deposits in the skin. Common causes of hyperpigmentation include sun exposure, inflammation, hormonal changes (such as melasma), and certain medications. Post-inflammatory hyperpigmentation (PIH), commonly occurs after an injury or inflammation of the skin, and periorbital hyperpigmentation, appears around the eyes, as dark circles. Understanding the cause of pigmentation is essential for effective treatment. Click to Read: Pigmentation in Indian Skin, Melasma Treatment.
Hyperpigmentation Treatment at Ambrosia Aesthetics, Mumbai
Ultracel Q+ HIFU for Pigment Rejuvenation
High-Intensity Focused Ultrasound (HIFU) is a non-invasive treatment that uses ultrasound energy to target deep layers of the skin. HIFU promotes collagen production and skin regeneration, which can help reduce the appearance of pigmentation and improve skin texture. “This treatment is particularly effective for rejuvenating the skin and addressing age-related pigmentation issues without the need for surgery”, says Dr. Sonavane.
Venus Viva MD Nanofractional Pigment Resurfacing
Venus Viva MD uses nanofractional radiofrequency technology to resurface the skin and treat pigmentation issues. This treatment creates micro-dermal wounds, triggering the body’s natural healing response and promoting the regeneration of healthy skin cells. Venus Viva MD is effective for reducing dark spots, improving skin texture, and achieving a more even skin tone with minimal downtime.
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Laser Treatments for Hyperpigmentation
Laser treatments are highly effective for reducing hyperpigmentation. They work by targeting the pigment in the skin, breaking it down, and allowing the body to naturally remove the pigment over time. Click to Read: Laser Skin Procedures, Laser Skin Lightening.
Q-Switch Laser for Hyperpigmentation
The Q-Switch laser is a popular choice for treating hyperpigmentation, including melasma and PIH. It is effective for pigmentation removal and has a shorter recovery time compared to other laser treatments.
CO2 Laser for Hyperpigmentation on Face
CO2 laser treatment can be used to remove black spots on the face, dark patches on the face, and other areas of hyperpigmentation. It’s particularly effective for hyperpigmentation on the cheeks, forehead, and nose. Click to Read: CO2 Laser Treatment.
Pico Laser for Dark Spots Reduction
Pico laser treatment is an advanced laser therapy that delivers ultra-short pulses of energy to target pigmentation. It breaks down melanin into tiny particles, which are then naturally eliminated by the body. “Pico laser is highly effective for treating dark spots, sunspots, and other forms of hyperpigmentation. It offers precise, fast results with minimal discomfort and downtime, making it a popular choice for pigmentation removal”, says Dr. Sonavane.
Intense pulsed light (IPL) for Pigmentation
This treatment is also known as photo rejuvenation or the photofacial. The IPL treatment targets pigmentation, freckles and age spots. It reduces pigmentation, treats broken capillaries and also has anti aging benefits. Click to Read: Intense Pulsed Light Treatment.

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Chemical Peels for Hyperpigmentation
Chemical peels are another effective method for treating hyperpigmentation. They work by exfoliating the top layers of the skin, promoting the growth of new, even-toned skin. Click to Read: Chemical Peel Treatment.
Glycolic Peel for Pigmentation
Glycolic acid peels are commonly used for treating hyperpigmentation. They are particularly effective for pigmentation on the face and can help remove black patches from the face. “We now have newer liposomal glycolic peels that are more potent, less sensitizing and cocktailed with other ingredients like glutathione, arbutin and tranexamic acid for safer and faster results”, says Dr. Sonavane.
Salicylic Acid for Hyperpigmentation
Salicylic acid is another option for chemical peels. It is effective for treating hyperpigmentation caused by acne (bacne hyperpigmentation) and can be used for facial peels for hyperpigmentation. “We now have salicylic peels in liposomal and gel technology with azelaic acid, resorcinol, ferulic acid and more for better result in fewer sessions”, says Dr. Sonavane.
Cosmelan Treatment for Hyperpigmentation
Cosmelan is a highly effective depigmentation treatment designed to reduce hyperpigmentation and improve skin tone. It works by inhibiting the enzyme tyrosinase, which is involved in the production of melanin, the pigment responsible for dark spots and uneven skin tone. The treatment involves the application of a professional-grade mask, which is left on the skin for several hours, followed by a home-care regimen to enhance and maintain the results. “Cosmelan is particularly effective for treating melasma, age spots, and post-inflammatory hyperpigmentation. It not only lightens dark patches but also helps to prevent new pigmentation from forming, offering a comprehensive solution for those struggling with persistent hyperpigmentation”, says Dr. Sonavane. Patients can expect significant improvement in skin clarity and a more uniform complexion after completing the treatment. Click to Read: Cosmelan Peel Treatment.

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PRP Treatment with Dermapen Microneedling for Hyperpigmentation
PRP (Platelet-Rich Plasma) treatment combined with Dermapen microneedling is an advanced and effective method for treating hyperpigmentation. GFC PRP utilizes the patient’s own blood, which is processed to concentrate the platelets and growth factors. These components are known to enhance healing and stimulate collagen production. When used in conjunction with Dermapen microneedling, which creates tiny micro-injuries in the skin, PRP penetrates deeper into the skin layers, accelerating the healing process and promoting more even skin tone.
“This combination helps to reduce dark spots, improve skin texture, and rejuvenate the overall complexion. The microneedling process itself also promotes collagen and elastin production, which further aids in reducing pigmentation and enhancing skin clarity”. This treatment is particularly beneficial for patients looking for a minimally invasive option with natural ingredients to achieve a more uniform and radiant skin tone”, says Dr. Sonavane. Click to Read: PRP Skin Treatment, Dermapen Microneedling Treatment.
Mesotherapy for Hyperpigmented Patches
Mesotherapy involves the microinjection of vitamins, enzymes, and other active ingredients directly into the skin to treat hyperpigmentation. This technique delivers nutrients precisely where they are needed, helping to reduce dark patches and improve overall skin tone. Mesotherapy can be customized to address specific pigmentation issues, making it a versatile option for those struggling with uneven skin color. Click to Read: Mesotherapy for Skin and Hair.
Skin Boosters for Pigment Reduction (NCTF)
Skin boosters like NCTF (New Cellular Treatment Factor) are injectable treatments that deliver hyaluronic acid and a cocktail of vitamins, amino acids, and antioxidants into the skin. These boosters enhance hydration, stimulate collagen production, and improve skin texture, which can help reduce the appearance of pigmentation. NCTF skin boosters are particularly effective for revitalizing dull, uneven skin and promoting a more radiant complexion.
Profhilo and Pigmented Skin
Profhilo is a unique injectable treatment that contains high concentrations of hyaluronic acid to hydrate and remodel the skin. “While primarily used for skin tightening and improving elasticity, Profhilo can also help reduce pigmentation by enhancing skin health and promoting a more even skin tone”, says Dr. Sonavane. It works by stimulating collagen and elastin production, resulting in a smoother, more youthful appearance. Click to Read: Profhilo Skin Injections.
Glutathione Injection in Hyperpigmentation
Glutathione injections are gaining popularity for their potential to lighten hyperpigmented skin. Since Glutathione is a powerful antioxidant, it inhibits melanin production and thereby reduces dark spots and promotes an even skin tone. Administered intravenously, these injections can provide faster and more noticeable results compared to oral supplements. However, it is essential to consult a good dermatologist like Dr. Sonavane to determine the appropriate dosage and ensure safety. Click to Read: Glutathione IV Injections.
Oral Supplements for Hyperpigmentation
Oral supplements can play a supportive role in the treatment of hyperpigmentation. Ingredients such as Vitamin C, Vitamin E, and Glutathione are known for their antioxidant properties, which help reduce oxidative stress and inhibit melanin production, thereby lightening dark spots. Other supplements like Polypodium leucotomos extract and niacinamide help in improving skin tone and protecting against UV-induced pigmentation. “While these supplements can enhance the effectiveness of topical treatments and other therapies, it is essential to consult a dermatologist before starting any new supplement regimen to ensure safety and efficacy tailored to individual needs”, says Dr. Sonavane.
Topical Treatments for Hyperpigmentation
Topical treatments are also widely used to manage hyperpigmentation. These include creams, serums, and lotions that contain active ingredients to lighten dark spots and even out skin tone.
Retinol for Hyperpigmentation
Retinol is a powerful ingredient that promotes cell turnover and reduces pigmentation. It is effective for hyperpigmentation on the face, neck, and body.
Kojic Acid for Pigmentation
Kojic acid is another popular ingredient that helps reduce pigmentation. It is often used in combination with other treatments for better results.
Tranexamic Acid for Hyperpigmentation
Tranexamic acid is effective for treating melasma and other forms of hyperpigmentation. It works by inhibiting melanin production and reducing dark spots.
How Much Does Laser Pigmentation Treatment Cost?
Hyperpigmentation Treatment | Cost (INR) |
---|---|
Pico Laser | 8,000 – 20,000 per session |
Q-Switch Laser | 6,500 – 15,000 per session |
Intense Pulsed Light (IPL) | 6,500 – 9,500 per session |
Glutathione and Tranexamic Acid Mesotherapy | 4,000 – 8,000 per session |
NCTF Skin Booster (New Cellular Treatment Factor) | 7,000 – 20,000 per session |
Ultracel HIFU for Pigment Rejuvenation | 15,000 – 25,000 per session |
Venus Viva MD RF Nanofractional Resurfacing | 15,000 – 30,000 per session |
Chemical Peels for Hyperpigmentation | 3,500 – 6,000 per session |
Cosmelan and Dermamelan Treatment | 35,000 – 45,000 per session |
Glutathione Tablets and Injections | 8,000 – 15,000 per session |
Profhilo Bio-Remodelling | 29,000 – 35,000 per session |
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Hyperpigmentation Treatment for Various Face and Body Areas at Ambrosia Aesthetics, Mumbai
Perioral Hyperpigmentation
What is Perioral Hyperpigmentation and Why Does it Occur?
Perioral hyperpigmentation refers to the darkening of the skin around the mouth, often caused by hormonal changes, post-inflammatory hyperpigmentation from acne, constant friction, sun exposure, and certain medications. People with darker skin tones are more prone to this condition due to higher melanin content.
Treatment Options for Perioral Hyperpigmentation
Topical treatments with hydroquinone, retinol, and kojic acid are effective in lightening the area. Regenerative and gentle chemical peels, like Bio-TCA peels, and non-invasive treatments such as the Ultracel Q+, can target deeper pigmentation in sensitive perioral skin. Daily use of broad-spectrum sunscreen is essential to prevent further pigmentation.
Underarm Hyperpigmentation
What is Underarm Hyperpigmentation and Why Does it Occur?
Underarm hyperpigmentation is the darkening of the skin in the armpit area, often caused by friction from clothing, frequent shaving or waxing, and certain deodorants. Hormonal changes, obesity, and genetic predisposition also play a role.
Treatment Options for Underarm Hyperpigmentation
Gentle skincare products and topical treatments containing niacinamide, alpha arbutin, and kojic acid can lighten the area. Chemical peels like Phenol-TCA peels and laser treatments such as the Pico laser are also effective. Maintaining good hygiene and using gentle, fragrance-free deodorants can help prevent further darkening. Click to Read: Underarm Skin Lightening.
Dark Spots and Patches on the Face
What are Dark Spots and Patches on the Face and Why Do They Occur?
Dark spots and patches on the face result from post-inflammatory hyperpigmentation, sun exposure, and hormonal changes, affecting skin tone. Conditions like melasma and acne scars also contribute to facial hyperpigmentation.
Treatment Options for Dark Spots and Patches on the Face
Topical treatments with hydroquinone, retinol, and vitamin C are effective for dark spot treatment. Chemical peels, such as SPA lightening acid peels, and laser treatments like the Pico or Carbon laser peel can help achieve a more even skin tone. Daily sunscreen use is crucial to prevent further pigmentation.
Lip Hyperpigmentation
What is Lip Hyperpigmentation and Why Does it Occur?
Lip hyperpigmentation refers to the darkening of the lips, caused by sun exposure, smoking, and certain medications. It can also result from post-inflammatory hyperpigmentation due to lip irritation or injury.
Treatment Options for Lip Hyperpigmentation
Treatments include lip lightening creams and balms with ingredients like kojic acid and alpha arbutin, and laser treatments specifically designed for the delicate skin on the lips. Chemical peels and lip boosters are also very effective. Click to Read: Lip Lightening Treatment.
Back Hyperpigmentation
What is Back Hyperpigmentation and Why Does it Occur?
Back hyperpigmentation, often caused by acne scars (bacne), sun exposure, and hormonal changes, results in dark patches on the back. Friction from clothing and prolonged sitting can exacerbate the condition.
Treatment Options for Back Hyperpigmentation
Topical treatments with hydroquinone, retinol, and glycolic acid can help lighten the skin. Chemical peels like SPA lightening, Bio-TCA and laser treatments like the Q-Switch laser are also effective. Good hygiene and regular exfoliation can help prevent further pigmentation. Click to Read: Back Acne Treatment.
Pigmentary Demarcation Lines
What are Pigmentary Demarcation Lines and Why Do They Occur?
Pigmentary demarcation lines are abrupt transitions between areas of lighter and darker skin, commonly seen in individuals with darker skin tones. They are often hereditary but can be exacerbated by hormonal changes and sun exposure.
Treatment Options for Pigmentary Demarcation Lines
Treatment options include topical creams with hydroquinone and retinol, chemical peels, and skin boosters like NCTF and Profhilo. Consistent use of broad-spectrum sunscreen can help prevent further demarcation.
Periorbital Hyperpigmentation
What is Periorbital Hyperpigmentation and Why Does it Occur?
Periorbital hyperpigmentation is the darkening of the skin around the eyes, often leading to dark circles. It can be caused by genetics, lack of sleep, allergies, thinning skin, excessive rubbing, sun exposure, and aging. This condition can make one appear tired or aged even when well-rested. Click to Read: What Causes Dark Circles in Indians?
Treatment Options for Periorbital Hyperpigmentation
Treatment includes lifestyle changes, skincare, and medical treatments. Daily use of broad-spectrum sunscreen prevents further pigmentation. Topical treatments with retinol, vitamin C, and hyaluronic acid can brighten and improve skin texture. Chemical peels like Resorcinol peels promote cell turnover, while laser treatments such as the Q-Switch laser target deeper pigmentation. Adequate sleep, managing allergies, and avoiding rubbing the eyes are crucial. Click to Read: Dark Circles Treatment.
Hyperpigmentation on the Neck
What is Hyperpigmentation on the Neck and Why Does it Occur?
Hyperpigmentation on the neck is characterized by dark patches, often caused by sun exposure, hormonal changes, and conditions like acanthosis nigricans. Post-inflammatory hyperpigmentation from acne or eczema, friction from clothing and jewelry, and certain medications can also contribute.
Treatment Options for Hyperpigmentation on the Neck
Treatments include topical creams with hydroquinone, retinol, and alpha arbutin to lighten dark patches. Chemical peels like Phenol and TCA help exfoliate and promote new skin growth. Laser treatments, including the Q-Switch laser, target deeper pigmentation. Daily use of broad-spectrum sunscreen is essential. Dr. Sonavane can develop a customized treatment plan for you.
Hyperpigmentation on the Buttocks and Inner Thighs
What is Hyperpigmentation on the Buttocks and Inner Thighs and Why Does it Occur?
Hyperpigmentation on the buttocks and inner thighs manifests as dark patches, often due to friction from clothing, chafing, and prolonged sitting. Other factors include hormonal changes, post-inflammatory hyperpigmentation from acne or other skin conditions, and obesity. Excessive sweating and poor hygiene can worsen it.
Treatment Options for Hyperpigmentation on the Buttocks and Inner Thighs
Treatment involves gentle exfoliation and topical creams with hydroquinone, alpha arbutin, and kojic acid. Regular exfoliation with salicylic acid or glycolic acid helps remove dead skin cells. Laser treatments like the Q-Switch laser are effective for deeper pigmentation. Maintaining good hygiene, wearing loose-fitting clothing, and using broad-spectrum sunscreen are also important. Dr. Niketa Sonavane can provide a tailored treatment plan.
Hyperpigmentation on the Arms and Legs
What is Hyperpigmentation on the Arms and Legs and Why Does it Occur?
Hyperpigmentation on the arms and legs appears as dark patches, often due to sun exposure, hormonal changes, post-inflammatory hyperpigmentation from acne or other skin conditions, and certain medications. Conditions like acanthosis nigricans and friction from clothing can also contribute.
Treatment Options for Hyperpigmentation on the Arms and Legs
Treatments include topical creams with hydroquinone, retinol, and kojic acid to lighten dark areas. Chemical peels, such as glycolic acid and salicylic acid peels, help exfoliate and promote even skin tone. Laser treatments like the Q-Switch laser target deeper pigmentation. Regular use of broad-spectrum sunscreen on exposed areas is crucial. Dr. Niketa Sonavane can create a customized treatment plan based on individual needs.

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